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ElevateBio

Powering the creation of cell & gene therapies at a speed the world deserves.

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    Gene Editing Technologies and R&D Overview

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AI & Protein Engineering

life edit


Combining our unprecedented CRISPR database with advanced AI to engineer next-generation gene editing systems for previously untreatable diseases.

// Gene Editing and
R&D Technologies

Unlocking Discovery with the Industry’s Largest CRISPR Dataset

We have one of the industry’s largest CRISPR collections, featuring millions of sequences and a catalog of more than 20 billion proteins and growing. This data-rich foundation gives our scientists a unique advantage in rapidly identifying novel targets that others miss, cutting months from traditional discovery timelines.

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AI-Powered CRISPR Design

Our sophisticated protein language models analyze vast datasets to uncover new CRISPR systems beyond what traditional methods could identify. Through our multi-year collaboration with Amazon Web Services (AWS), we train and execute these models at scale. By combining generative AI with our proprietary experimental data, we can predict, design, and optimize both naturally occurring and synthetic CRISPR proteins with unprecedented precision.

Expanding Gene Editing’s Therapeutic Reach

We’re taking on the challenge of expanding CRISPR’s application beyond the small number of single-gene conditions addressed by first-generation therapies. Our AI-driven approach is accelerating development for thousands of more complex monogenic disorders as well as polygenic diseases, paving the way for potentially curative treatments across a much broader range of therapeutic areas. Where others see limitations, we see opportunities to engineer synthetic solutions tailored for each disease.

Precision Optimization at Scale

Our platform systematically addresses key challenges in CRISPR development: editing efficiency, target specificity, tissue delivery, and off-target activity. Through our AWS collaboration, we combine PLM-driven active learning with targeted experimental screens – including DNA binding, nuclease activity, base editing, reverse transcriptase editing, and off-target analysis – to optimize protein performance. This approach allows us to rapidly iterate designs and explore a wider design space than conventional methods, significantly reducing both time and cost of protein discovery while improving therapeutic potential.

How Life Edit is using AI to expand the therapeutic boundaries of CRISPR

By Shaorong (Ron) Chong, Ph.D., VP of Technology Development, and Joel Parker, Ph.D., VP of Computational Biology, Life Edit Therapeutics

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Elevated Insights

From gene editing to biomanufacturing, learn more about the cell and gene therapy industry from our team of industry-leading experts.

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The Breadth of our Platform and Technology Offers Unmatched Editing Capabilities

Gene Editing Toolbox

We have a powerful suite of proprietary gene editing technologies to accelerate the development of life-changing and curative therapies for patients.

Learn about our editing tools

Applications & Delivery

We have broad therapeutic delivery capabilities, including viral and non-viral delivery platforms to provide flexibility in therapeutic design and application, unlocking new possibilities for addressing a wide range of diseases and disorders.

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Partner with ElevateBio®

Wherever you are in your cell and gene therapy product lifecycle, we can strengthen and accelerate the development of your transformative therapies with our enabling technologies unmatched manufacturing capabilities.

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