The LentiPeak™ Platform
Our proprietary lentiviral vector (LVV) platform is customized to meet your specific development needs.
We offer our partners a suspension-based, scalable lentiviral vector production platform.
Speed
Streamlined Tech Transfer between PD and cGMP manufacturing with aligned unit operations, equipment, bill of materials and analytics
Available cGMP capacity without waiting time
Parallel development with cell processing activities for ex-vivo programs
Control Strategies
Efficient supply chain management & risk mitigation
Comprehensive regulatory support package
Integrated analytical support with panels of established testing methods in-house
Expertise
Process utilizes a 4-plasmid 3rd gen LV system and a HEK 293 suspension cell line
Pre-established cGMP documentation and trained technical team
Proven platform performance with various CAR and TCR constructs at multiple production scales
LentiPeak™ Platform: Process Overview
Process
- HEK293 cell line
- Suspension based, serum free
- Transient Transfection
System
- 3rd Generation LV plasmid system
- Accommadates a large range of GOI sizes
- Supporting analytics
Productivity
- High functional titers
- 1.00E+08 to 1.00+09 TU/mL
Learn More About our Work in Lentiviral Vector Development
Elevate Insights whitepaper on our LVV capabilities
BioPharm International publication on the strategies and tactics for designing an ideal lentiviral vector platform
Poster on our lentiviral vector platform presented at the fall 2022 BioProcess International Conference
“De-risking lentiviral vector production using a robust, scalable, suspension-based platform” webinar
LentiPeak® fact sheet
ElevateBio BaseCamp®
Where the Innovation Happens
BaseCamp is the innovation engine where technology, expertise, operations, processes, and GMP manufacturing come together to overcome industry challenges and accelerate the development of advanced therapies.
Basecamp
Cell Platform Manufacturing Processes
- Cell therapy process tools and equipment
- Platform processes for CAR-T and TCR-T
- Modular unit operations to accommodate multiple cell types
Vector Platform Manufacturing Processes
- Suspension-based upstream process for LVV and AAV
- Platform upstream & downstream lentiviral process for CAR-T, TCR-T and in vivo lenti viral vectors
- Wide array of vector services
Process Development & Analytics
- Industry leading Process Development expertise
- Directly scalable processes from PD to GMP
- Process optimization with scale up/down models
- State of the art, in-house rapid QC release test methods and analytics
Manufacturing & Automation
- End-to-end solutions for cGMP manufacturing
- Multiple automated systems for real-time review of data and product release
- CMC regulatory support
- Aphoresis support
How can we support your project goals?
// Connect with us
